Both teams will be coming off tough Week 12 matchups as they enter their holiday face-off. The Cowboys host the Eagles – the team holding the NFC's No. 1 seed through 11 weeks – one week before Thanksgiving. The Chiefs host the Colts – the team that held the AFC's No. 1 seed as recently as Week 10 before their Week 11 bye.

Week 12 of the 2025 NFL season is here, with teams looking to position themselves for the postseason over the final seven weeks of the year. There are plenty of story lines for today’s games, including the 5-5 Kansas City Chiefs trying to fight their way into a postseason position against a surprising 8-2 Indianapolis Colts,