A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl group (C=O) to a nitrogen atom. They're so ubiquitous that 117 of the top ...

Developed in the Pentelute Lab within MIT’s Department of Chemistry, Amide’s complex peptide manufacturing platform expands what is possible in peptide drug design by offering reliable linear ...

Chemists have been using the Schmidt reaction, which transforms aldehydes and ketones into amides, for nearly 100 years. But the reaction has a downside that prevents it from being widely used: it ...

Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...