An aging mouse forgets where the hidden platform sits in a water maze. But strip away a single iron-storage protein from its hippocampal neurons, and the animal navigates like a younger version of ...

Scientists have uncovered a powerful new clue in the mystery of brain aging: a single protein called FTL1. In aging mice, higher levels of this protein weakened connections between brain cells and led ...

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, regional differences, and potential biomarkers of brain aging. More than 57 ...

Aging brains are often misunderstood. Older adults go through changes neurologically, but it does not mean intelligence is lost. Now, University researchers are examining how surgery and aging can ...

Aging may "erase" the epigenetic markers that control gene expression in the brain, and this may snowball to cause unintended consequences, a new mouse study suggests. Tiny chemical messages attached ...

A newly identified protein may hold the key to rejuvenating aging brain cells. Researchers found that boosting DMTF1 can restore the ability of neural stem cells to regenerate, even when age-related ...

Geneticist Anne Brunet explores what aging really is, how lifestyle choices might influence longevity, and the promising frontiers of aging research. Aging is a process that affects us all. But how ...

The statistics surrounding dementia and Alzheimer’s are alarming. According to the Alzheimer’s Association, more than 7 million Americans are living with Alzheimer’s, a disease that is a form of ...

Age is more than just one number. While neuroscientists used to think of cognitive aging as a single trendline, they now realize that vast individual differences require a more predictive and ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...