Researchers analyze 2.2 million genomes to show that addiction risk is primarily driven by broad genes affecting brain wiring and impulse control, not drug-specific traits.

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process ...

No level of alcohol is safe for the brain and even light drinking is linked to an increased risk for dementia, results of a large observational study suggested. The research combined observational ...

New evidence from large-scale genetic and cohort studies reveals that alcohol increases dementia risk across the dose range, overturning the myth of “safe” moderate drinking. Study: Alcohol use and ...

A novel approach has identified drugs in current use that could be repurposed for treating alcohol use disorder (AUD). In 2023, 28 million US adults had experienced AUD in the past year. But only ...

Chronic pancreatitis is now recognized as a complex fibroinflammatory disorder involving genetic, environmental, and metabolic factors.

Researchers at the University of Helsinki, Finland, have found a genetic variation, which associates with the damage caused by maternal alcohol consumption. This genetic variation clarifies the role ...

A vast majority of American adults say they have consumed alcohol at some point — yet experts warn that alcoholic beverages could be a "gateway drug" to more harmful substances. More than 84% of ...