Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

While NAMs could revolutionise preclinical development, experts warn that they won’t phase out animal testing for “a long ...

A research team led by the Institut de Neurociències at the UAB has managed to generate and validate a new animal model. This model enables the examination of the initial phases of Parkinson's disease ...

The humble lab mouse is an essential research tool, helping researchers understand the biological processes that underpin disease development and progression. The ability to observe disease pathology ...

Scientists usually use animal models when studying Parkinson's disease because these models mimic the disease well. They are ...

Medical researchers have used animals, particularly mice, to mimic disease and study biological phenomena. The origin of mice as a standard model system for scientific research can extend back to the ...

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure. Another example, ...

Animal models continue to be a mainstay of basic research and preclinical studies. But since animals such as mice only approximate humans, they may generate findings of limited clinical relevance.

Animals have been used for medical research for thousands of years, dating back to ancient Greece where the first dissections were performed. These days, one of the main uses of animals is to ensure ...