Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse disorder as of ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...

Nicotine from e-cigarettes can affect the brains of young people.

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Emma Fenske, DO, Oregon Health & Science University (THE CONVERSATION) Addiction is ...

(THE CONVERSATION) Addiction is one of the most common and consequential chronic medical conditions in the United States. Nationwide, more than 46 million people met the criteria for a substance abuse ...