Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...

Towards the end of 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared on the scene, and practically shut down the world for the next several months. Since then, a slow and ...