Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells ...

Using CRISPR co-culture screens, researchers found that deleting CHD1 and MAP3K7 makes tumor cells more vulnerable to immune ...

The deletion of two cancer genes, CHD1 and MAP3K7, improves how well tumors respond to cancer immunotherapy and could be used ...

The following filter criteria for genes differentially expressed were used: PDAC versus normal pancreas (bulk tissue), PDAC versus normal pancreas (microdissected normal ductal cells), and PDAC versus ...

By profiling gene expression in colon cancer cell clones, researchers identified signatures linked to metastatic risk and built an AI model that predicts spread and recurrence with high accuracy.

The NCCN guidelines now include MammaPrint for identifying HR+/HER2- early-stage breast cancer patients who may benefit from ...

PCR-based techniques have transformed how scientists analyze transcripts’ translational applications in cancer and neuroscience research.

Brazilian researchers have identified previously unknown forms of a protein linked to breast cancer. The discovery ...

A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...