Cell-free protein synthesis (CFPS) represents a transformative technology in which the molecular machinery of transcription and translation is extracted from living cells and employed in a controlled ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound.

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

A group of natural compounds attracting attention for their anti-aging potential has a dark side. New research shows how a ...

The yeast Kluyveromyces lactis (K. lactis) could become a highly productive, sustainable, cost-effective energy source for cell-free protein synthesis (CFPS) as biopharmaceutical manufacturers strive ...

Scientists developed a new mRNA platform that keeps vaccines and therapies effective in older adults and patients with obesity, where current treatments often lose potency.

Nerve cells have amazing strategies to save energy and still perform the most important of their tasks. Researchers from the University Hospital Bonn (UKB) and the University of Bonn as well as the ...

Scientists have identified a critical breakdown in the cellular machinery that produces proteins in aging brains.

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

In recent years, mammalian synthetic biology has made significant strides, especially in controlling gene expression and designing complex cellular behaviors. Researchers have now begun to apply these ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...