Continued process verification (CPV) is the third stage of the product lifecycle of any medicine either within the small or large molecule arena. The CPV is the subsequent step to process design ...
Researchers at the University of Liège (BE) have designed a high-performance, open-access continuous flow process to safely produce key antibacterial drugs from bio-based furfural. The results of the ...
Continuous manufacturing is finally gaining traction in the pharmaceutical industry, but development of the necessary production technologies is, fittingly, a continuous process. Ultimately, the drawn ...
The U.S. Army is evaluating a new manufacturing approach that could speed up missile ...
A photo of technicians working in front of a process train. Novartis's continuous manufacturing center in Basel, Switzerland, replicates an end-to-end manufacturing process developed at the ...
Using continuous processing instead of batch-based processing provides therapeutic manufacturers with a number of advantages. For example, the continuous approach can ...
We used a 5-L B-DCU bioreactor (Sartorius, Göttingen, Germany) with a working volume of 2 L. The setup, technical equipment and control loops are summarized in Fig. 1. The culture broth was stirred in ...
DIANT is a startup co-founded by Antonio Costa, Ph.D. and Diane Burgess, Ph.D. In 2020, DIANT licensed their core manufacturing technology from UConn and was granted a patent on the technology earlier ...
Continuous manufacturing has been a hot topic for years. With COVID-19 highlighting the fragility of global pharmaceutical supply chains, the approach could finally get its moment to shine.
This Comment explores why continuous crystallization, despite its success in other industries, remains underutilized in pharmaceutical manufacturing. Among other challenges, we highlight two core ...
A new study demonstrates the first cost-effective method for producing cultivated meat. The study shows that continuous manufacturing addresses the key challenges of scalability and cost, potentially ...