This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

How does DNA structure itself from the very first moments of life? A team of researchers has just observed that DNA adopts a defined three-dimensional architecture much more rapidly than ...

DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism. What’s not captured by this analogy is the fact that our DNA ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone cross-links (DHCs) occur frequently within ...

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...