Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While numerous studies have shown that social status profoundly impacts mental health and ...

Could coffee help to counteract some of the effects of alcohol on the brain, and potentially limit the risk of addiction? That's what's suggested by a new study of how caffeine interacts with the ...

India, May 31 -- Why do some people become addicted to nicotine after relatively little exposure, while others are able to ...

New findings published in the journal Nature Neuroscience have shed light on a mysterious pathway between the reward center of the brain that is key to how we form habits, known as the basal ganglia, ...

GLP-1 receptor agonists, already used for Type 2 diabetes and obesity, show promise in reducing alcohol and drug-seeking ...

Social rank regulates methamphetamine-seeking behavior by modulating the mesocortical and mesolimbic dopamine pathways, and winning experiences can remodel these circuits to suppress drug-seeking. In ...

LOS ANGELES — Maybe you'd like to spend time on hobbies or hang out with friends, but nothing feels as exciting and engaging as it used to –– so you just squander another hour on social media. Your ...

Methamphetamine doesn't just spike levels of the pleasure-inducing hormone dopamine in the reward pathways of the brain—it also provokes damaging brain inflammation through similar mechanisms.

Dopamine is one of the most extensively studied chemical messengers in the human brain, and yet scientists are still figuring out how it works to accomplish so much. For years, the classic view has ...