Nearly every cell in your body depends on mitochondria to survive and function properly. Mitochondria provide 90% of our ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, ...

The tumor microenvironment (TME) is a major obstacle that limits effective cancer treatments. Various cells around the tumor promote immunosuppression and prevent the immune system from targeting ...

Many of us remember from high school biology class that mitochondria are the cell's "power plants." These small kidney-bean-shaped structures are what convert nutrients from food into ATP—the cell's ...

Chronic kidney disease (CKD) affects more than 700 million people worldwide and is caused by genetic and environmental ...

James McCully was in the lab extracting tiny structures called mitochondria from cells when researchers on his team rushed in. They’d been operating on a pig heart and couldn’t get it pumping normally ...

Mitochondria are well known as energy suppliers, and powerhouses of cells, but they have other crucial functions as well. One of those functions is outcompeting pathogens for resources, according to ...

I always wanted to understand life. What moves us? What allows us to heal and thrive? And what goes wrong when we get sick or when we eventually stop breathing and die? My search for answers to these ...

Researchers at the University of Jyväskylä have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to ...