Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Almost 1,500 genes have been implicated in intellectual disabilities; yet for most people with such disabilities, genetic causes remain unknown. Perhaps this is in part because geneticists have been ...

The human genome may contain more protein-coding genes than prior analyses suggested. A study published last month (May 29) on BioRxiv provides an expanded database of approximately 5,000 novel ...

For millennia, evolution has intrigued many great thinkers, prompting questions about how new traits emerge as species adapt over time. Then, attention shifted to natural selection and the inheritance ...

Thousands of previously “invisible” microproteins—tiny chains of fewer than 100 amino acids—can profoundly change human biology when mutated. A fundamental discovery is overturning decades of ...

The FDA granted fast track status to VectorY’s VTx-002, an antibody gene therapy targeting TDP-43 protein aggregates in ALS.

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

Researchers from Radboud university medical center and University of Basel have discovered new genetic causes of inherited ...

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...