(koto_feja/Getty Images) Carrying one or two copies of the APOE4 gene variant significantly increases the risk of developing ...

Most people think of Alzheimer’s disease as an illness of aging. But in fact, the brain changes that characterize it begin ...

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Memory loss often feels like something that arrives late in life. In reality, the story may begin much earlier, long before ...

Alzheimer's disease is strongly associated with a genetic variant widely known as APOE4. This is one variation of the APOE gene... | Genetics And Genomics ...

How does Alzheimer’s target specific brain cells? Researchers are building a multiscale model of the hippocampus to map neuronal loss and cognitive decline.

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, regional differences, and potential biomarkers of brain aging. More than 57 ...

High levels of calcium are toxic to cells and contribute to loss of neurons in Alzheimer’s disease. A new JCI Insight study identifies a mechanism through which the young brain protects itself against ...

A new study links tau pathology to disrupted sleep in Alzheimer's disease. Sleep expert Dr. Wendy Troxel discusses how ...

More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as "lipoid granules," along with the buildup of amyloid-beta (amyloid) plaques and tau protein tangles.

Women are more likely than men to be diagnosed with dementia. While researchers have some idea of the factors that elevate risk, it’s still not entirely clear why this happens. But a recent study ...

Sitting for too long increases dementia risk, while getting regular exercise could protect brain health in the long-term, a ...