DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...
Imagine you work for a hypothetical gene synthesis company, one of dozens around the world that manufacture tiny strands of custom nucleic acids like DNA for customers in academia and industry. DNA ...
Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?
A portion of our genome that was once dismissed as being “junk” may actually play an important role in regulating gene expression, new research suggests. According to the work of an international team ...
All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...
Caption main figure: The rigid base-pair model is forced, using 28 constraints (indicated by red spheres), into a lefthanded superhelical path that mimics the DNA conformation in the nucleosome.
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