Phase 3 trials showed Vanrafia slowed the decline in kidney function for adults with the progressive autoimmune kidney disease, IgA nephropathy.

Kidney aging rarely draws attention until something goes wrong. Over time, these organs quietly lose strength, filter less efficiently, and struggle to keep the body balanced.

A total of 340 biopsy-confirmed IgAN patients were randomised to daily oral Vanrafia or a placebo for approximately 132 weeks.

It’s déjà vu all over again. Just as the kidney disease space becomes increasingly competitive, Novartis has found itself intending to turn a statistical miss into a regulatory win. | It’s déjà vu all ...

Fish treated with SGLT2 inhibitors maintained healthier kidneys as they aged. Their kidneys preserved denser networks of capillaries, retained a stronger filtration barrier, and showed more stable ...

Older adults living with heart failure with preserved ejection fraction (HFpEF) are frequently labeled as having chronic ...

Kidney disease often creeps in silently, and many patients aren’t diagnosed until major damage is already done. New research ...

Aims Heart failure (HF) often coexists with chronic kidney disease (CKD), impacting prognosis. This study aims to evaluate ...

Currently, patients who have had a kidney transplant must take a cocktail of pills every day for the rest of their lives. These standard immunosuppressants prevent the immune system from attacking the ...

Originally developed as a more-potent follow-up to Roche's long-established CD20-directed antibody Rituxan (rituximab) for ...

Many people assume that if a supplement is labelled “natural,” it must be safe. But that belief can be misleading. Several ...

Your kidneys work tirelessly every day, filtering approximately 120 to 150 quarts of blood to produce about 1 to 2 quarts of urine. These vital organs remove waste products, excess water, and toxins ...