Shimadzu Scientific Instruments announces the release of the Nexera MX ultra-high speed LCMS system for multiplex analysis. Equipped with Nexera MX Dual Stream Technology (MX-DST), the system can ...

This detailed overview explains the technical mechanisms of LC-MS proteomics, including peptide separation, ion generation, ...

Synthetic oligonucleotides have been used as critical research reagents in the biotechnology industry since its beginning in the 1970s. Their increasing use first led to the formation of many core ...

The success of any large-scale proteomics study is fundamentally determined at the sample preparation stage, which serves as the critical bridge between the biological system and the analytical ...

Mass spectrometry has been the detection technique of choice for pharmaceutical analysis for many years. It is a powerful means of analysis that allows complex pharmacological mixtures to be separated ...

The structure of N-linked glycans can play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. This makes the ...

In this episode BioTechniques Digital Editor, Tristan Free speaks to Annie Evans, Director of R&D and David Foster, Vice President of Data and Informatics at Metabolon (NC, USA) about the latest ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

How is LC-MS performed? The sample first undergoes ionization before entering the mass spectrometer. Commonly used ionization methods are electrospray ionization and atmospheric pressure chemical ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...