A mouse model study has identified new cellular processes controlling development of the small valves inside lymphatic vessels, which prevent lymph fluid from flowing the wrong way back into tissues.

A preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. Valve loss or dysfunction that disrupts the flow of lymph fluid is strongly ...

The lymphatic system is a network of branching vessels that regulate fluid balance and support the immune system. Its smallest capillaries, comprised of a single endothelial cell layer, must stay ...

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine's resident ...

In its response to pathogens and vaccines, our immune system relies on dendritic cells. These white blood cells patrol the body's tissues, collect components of pathogens and vaccines and transport ...

Predictive factors of ductal spreading in preoperative breast cancer patients. Background: Triple-negative breast cancer (TNBC) comprises of about 15%-20% of all breast cancer cases. Many studies have ...

The 2015 discovery of lymphatic vessels in the brain’s meninges threw open a door to seeing how this still-mysterious organ clears waste. Subsequent work showed that these vessels, which reside in the ...

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms ...

Tampa, FL (Aug. 9, 2021) --A University of South Florida (USF Health) preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. The research, ...