Mounting evidence points to a link between new-onset allergies and Long COVID, with mast cell activation syndrome as a ...

Patients with mast cell activation disorders safely tolerated doses of four of the COVID-19 vaccines, although there was a relative increase in hypersensitivity and anaphylactic reactions, according ...

Allergic diseases represent a major global health burden, placing significant strain on health care systems worldwide. Severe ...

Eosinophils and mast cells are two types of immune cells with critical roles in responding to foreign assaults. When these cells do not function properly, several disease outcomes can develop (e.g.

Researchers discovered Fab antibody fragments that target the IgE Cε2 domain, destabilizing IgE–FcεRI complexes on mast cells. In mouse models, allergic responses were significantly reduced. This ...

Jasper Therapeutics’ monoclonal antibody briquilimab is effective at preventing mast-cell induced anaphylaxis and asthma in mice, new data suggest. In an oral presentation and two posters at the ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...

Blueprint Medicines’ focus on Ayvakit continues to pay off, which has ample untapped revenue potential in advanced and indolent systemic mastocytosis. Additionally, their pipeline includes other ...