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Ageing slows brain protein clearance and shifts synaptic waste to microglia
By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...
For a long time, neuroscientists treated this forgetting as a cognitive glitch or a simple lack of brainware maturity. But a ...
In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence ...
In chronic neurodegeneration associated with prion disease, reactive microglia adopt a highly mobile, neuron-by-neuron surveillance strategy, replacing homeostatic process-based monitoring with ...
A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering human ...
Recently approved Alzheimer’s drugs offer a step forward for treating the disease, but new therapeutic strategies are needed to complement them and provide personalized therapeutic approaches. Mass ...
Anxiety is often described as a whole‑brain problem, but a series of mouse experiments suggests that, in some cases, a single misfiring circuit can tip the balance between calm and fear. By nudging ...
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