KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...
The DNA damage from ionizing radiation (IR) erupting from the Chernobyl nuclear disaster of 1986 is showing up in the ...
A reanalysis of whole-genome data from 130 children conceived after the Chernobyl disaster has identified a statistically ...
They found an average of 2.65 clustered de novo mutations (cDNMs) per child, compared to 0.88 cDNMs in children of unexposed ...
Cancer cells carry thousands of mutations, but not all mutations are created equal. Some make tumors highly visible to the ...
Fast functional testing of genetic variants, from newborn genomes to disease models like zebrafish, is transforming ambiguous DNA findings into confident, real‑time treatment decisions.
A hallmark of Parkinson's disease is the buildup of Lewy bodies—misfolded clumps of the protein known as alpha-synuclein.
Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth.