Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

The authors review developments in wet granulation using a twin-screw extruder. As a result of changing philosophies towards continuous manufacturing, new equipment is being introduced into ...

Using a specific addition method to wet the powder bed in twin-screw granulation using a foam binder improves robustness for continuous solid-dosage drug product manufacturing. In less than a decade, ...

Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Spatial filter techniques, along with delivering real-time particle size measurement, offer several further attractions such as simple hardware requirements, ease of use and reasonable commercial cost ...