Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

A new study shows p62-mediated Mallory-Denk body formation is an adaptive, protective response to alcohol-induced liver ...

The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington's, Alzheimer's and Parkinson's. But to the human eye, proteins that are ...

Amyloid beta and tau proteins compete for the same binding sites on microtubules in neurons, suggesting that displacement of ...

A structural protein best known for building the internal scaffolding of cells may double as a natural defense against the toxic protein clumps that drive Alzheimer’s and Parkinson’s diseases. New ...

A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates found in Alzheimer's disease, pointing toward a new potential therapeutic ...

A team of researchers at Kumamoto University has uncovered a groundbreaking mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's Disease ...

Explore the promising early results of PRI-101, a new treatment for Parkinson's disease aimed at targeting neurodegeneration.

In patients with Huntington’s disease, proteins misfold and clump together. Researchers imagine the treatment could potentially someday be administered as a once-weekly injection to delay disease ...

Scientists can now zoom in on protein segments in living cells, tracking changes linked to early disease and aiding drug screening for aggregation disorders. The research team engineered a fluorescent ...