Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and ...

These elusive sequences are known to impact viral replication, host immune responses, and gene regulation, yet their detection requires experimental methods beyond current computational tools.

Analyzing thousands of proteins from a single drop of blood is no longer science fiction. High-throughput proteomics has transformed biomarker discovery by enabling simultaneous profiling of thousands ...

The first-in-human phase 1/2 study of TSN1611, a highly selective KRAS G12D inhibitor, in patients with advanced solid tumors. Seizure-related homolog 6 (SEZ6) expression and ctDNA methylation ...

A novel RNA sequencing technology enables simultaneous quantification of intracellular proteins and transcriptomes, which could transform cancer research and therapeutics. Single-cell RNA sequencing ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

Membrane proteins are the gateway to cells and are involved in many critical functions. Each membrane protein is unique, and their complexity makes it difficult to fit into a standardized expression ...

The “dark proteome” includes uncharacterized proteins that may influence cancer growth, immune evasion, and therapy ...