A deep dive into the Fc–FcR axis as a therapeutic anchor in autoimmune disease, examining immune signaling and drug ...

Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...

In a recent study, Alexander von Humboldt Professor Jijie Chai at the University of Cologne and his team together with MPIPZ researchers have succeeded for the first time in reconstructing the ...

From studies conducted on animals, evidence has emerged that both neutralizing activity and Fc-mediated effector functions of neutralizing antibodies provide some levels of protection against the ...

A collaborative study on a plant intracellular immune receptor not only shows how an important resistance protein is activated during pathogen infection but also reveals some common operational ...

Chimeric antigen receptor natural killer (CAR-NK) cell therapy is emerging as a promising next-generation immunotherapy with the potential to overcome key limitations of current chimeric antigen ...

A synthetic protein has demonstrated the ability to discriminate between cancerous and non-cancerous cells in vitro, showing potential for advances in personalized treatments. Researchers from ...

Organisms sense and respond to changes in the environment through signal transduction pathways. Pathways like highly conserved Mitogen-Activated Protein Kinase (MAPK) pathways are composed of sensor ...

Research teams explore the activation of plant immune receptors by pathogens. In a recent study, Alexander von Humboldt Professor Jijie Chai at the University of Cologne and his team together with ...