Cats are much more than just our four-legged companions; new research now explains how our furry friends could also aid the development of new drugs for HIV. Researchers have deciphered the structure ...

Sequence variation is particularly relevant to infectious pathogens that mutate in response to antimicrobial therapy. Sequence variations in human immunodeficiency virus (HIV)-1 reverse transcriptase ...

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) are a class of antiretroviral drugs that help manage HIV by blocking a key enzyme the virus needs to replicate its RNA into DNA. There ...

Viral reverse transcriptase (RT) plays a critical role in replication (e.g., retroviruses, that reverse transcribe RNA templates into complementary DNA) and genome mutations (e.g., ...

With two catalytic activities and many substrates, how does HIV's reverse transcriptase enzyme know what to do to which substrate? Zooming in on the enzyme's molecular interactions provides ...

With Gift Aid, your generous donation of £10 would be worth £12.50 at no extra cost to you. Yes, I want to Gift Aid any donations made to NAM now, in the future and in the past four years I am a UK ...

BRANFORD, CT / ACCESSWIRE / May 28, 2024 / RNAConnect, a pioneering life science tools company, officially announced the commercial launch of UltraMarathonRT™ (uMRT), a next-generation, ...