Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

A time-delay circuit enables precise control over the division of synthetic DNA droplets, which mimic biological Liquid-Liquid Phase Separation (LLPS) droplets found in cells. By utilizing a ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...

Researchers created artificial kinetochore structures that reduce chromosome separation errors during meiosis in aging egg cells. By lowering microtubule pulling force, the approach helped maintain ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

Scientists have uncovered how brewer’s yeast developed its unusually tiny centromeres, the DNA regions that guide chromosome separation during cell division. By studying related yeast species, ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...

By simulating the life cycle of a minimal bacterial cell, from DNA replication to protein translation to metabolism and cell division, scientists have opened a new frontier of computer vision into the ...

Chemists induced a cell-like behavior in molecular assemblies called vesicles. They used a sacrificial chemical fuel to make the vesicles divide into smaller versions of themselves. While this process ...

Many cellular functions in the human body are controlled by biological droplets called Liquid-Liquid Phase Separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside ...