Multiple sequence alignment (MSA) lies at the heart of comparative genomics, structural biology and evolutionary inference. By arranging three or more nucleotide or amino acid sequences in a matrix, ...
DNA sequencing has changed biology like nothing else since the origin of species theory. In particular, the way we investigate microbial life has fundamentally changed. Today, we are able to sequence ...
Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...
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