The combination of Cas9, guide RNA and repair template DNA can induce precise gene editing and the correction of genetic diseases in adult mammals. However, clinical implementation of this technology ...

This is a preview. Log in through your library . Abstract Bacteriophage T5 is known to contain several unique single-strand interruptions in only one strand of the duplex DNA. Analysis of labeled ...

A stem cell biologist from City University of Hong Kong (CityU), together with his collaborators, has developed a novel strategy, called in vivo priming, to 'train' the stem cells to stay strong after ...

The radiosensitivity of mouse hepatocytes in vivo was measured in terms of clonogenicity or chromosome damage (micronucleus production). Within 24 h of irradiation there was a dose-dependent increase ...