Europe PMC

BNT162b2 Vaccine: possible codons misreading, errors in protein synthesis and alternative splicing's anomalies

BNT162b2 vaccine against Covid-19 is composed of an RNA having 4284 nucleotides , divided into 6 sections , which bring the information to create a factory of S Spike proteins , the ones used by ...
Europe PMC

Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors.

Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors.
Europe PMC

Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models.

Authors Ramezani-Rad P 1, 2 Cottrell CA 2 Marina-Zárate E 1, 2 Liguori A 2 Landais E 2 Myers A 1, 2 Lee JH 2 Baboo S 2 Flynn C 2 McKenney K 2 Salcedo E 2 Zhou X 2 Kalyuzhniy O 2 Georgeson E 2 Phelps N ...
Europe PMC

Characterization of birefringence dispersion in polarization-maintaining fibers by use of white-light interferometry.

A new method for measuring the birefringence dispersion in polarization-maintaining fibers (PMFs) with high sensitivity and accuracy is presented. The method employs white-light interferences between ...
Europe PMC

A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers.

Antibiotics (ABX) compromise the efficacy of programmed cell death protein 1 (PD-1) blockade in cancer patients, but the mechanisms underlying their immunosuppressive effects remain unknown. By ...
Europe PMC

The role of data science in healthcare advancements: applications, benefits, and future prospects.

The role of data science in healthcare advancements: applications, benefits, and future prospects.
Europe PMC

SARS-CoV-2 S1 Protein Persistence in SARS-CoV-2 Negative Post-Vaccination Individuals with Long COVID/ PASC-Like Symptoms

SARS-CoV-2 S1 Protein Persistence in SARS-CoV-2 Negative Post-Vaccination Individuals with Long COVID/ PASC-Like Symptoms ...
Europe PMC

Seroprevalence of certain bacterial and viral infections among the Irula tribal population of Marakkanam, Tamil Nadu state, India.

Observation The seroprevalence of leptospirosis and hantavirus may be attributed to their professional exposure to rodent that they catch in the open field and the syphilis, hepatitis B and HIV ...
Europe PMC

Advances in research of the chem istry and bioactivity of juglans plants

The research into the chemistry and biological activity of the genus juylans L. plants were reviewed from two aspects of m ajor metabolites such as naphthoquinones, flavonoids, and diary lheptanoids ...
Europe PMC

Late adverse effects and quality of life in survivors of testicular germ cell tumour.

Currently, ~95% of patients with testicular germ cell tumour (TGCT) are cured, resulting in an increasing number of TGCT survivors. Although cured, these men face potential late adverse effects and ...
Europe PMC

Efficacy and safety of substitute vincristine with vindesine in R-CHOP- like regimen in the treatment of newly diagnosed DLBCL, a real-world study

The replacement of doxorubicin with other anthracyclines like epirubicin, pirarubicin, or liposomal adriamycin in the R-CHOP regime showed non-inferiority for DLBCL. Replacing vincristine with ...
Europe PMC

Reference genome assemblies reveal the origin and evolution of allohexaploid oat

Common oat (Avena sativa) is one of the most important cereal crops serving as a valuable source of forage and human food. While reference genomes of many important crops have been generated, such ...