Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Aerobic glycolysis dominates lesion bioenergetics, with lactate promoting histone lactylation, M2 macrophage polarization, ...

The field of nutrition science increasingly recognizes the role of dietary bioactives, non-nutrient compounds in foods such as polyphenols, carotenoids, ...

Aging is associated with progressive alterations in endocrine signalling that disrupt the regulation of energy balance and metabolic homeostasis. Changes in ...

(A) The TCA cycle is a central metabolic hub that integrates energy production, biosynthesis, and redox functions. It supports ATP production through the generation of the reducing equivalents NADH ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, ...

As a highly differentiated sensory organ, the maintenance of the eye's physiological functions relies on rigorous metabolic regulation. The ...