and its competitors are a 5' cap-trapping step and a class II restriction enzyme (MmeI), which cleaves DNA 20/18 bp downstream of the recognition site to create the sequence tag. (Reprinted from T.
Phase I and Pharmacokinetic Study of NSC 655649, a Rebeccamycin Analog With Topoisomerase Inhibitory Properties ABSTRACT: Cancer is a genetic disease. As such, our understanding of the pathobiology of ...