Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 4 (January 26, 2016), pp. 966-971 (6 pages) The mitotic (or spindle assembly) checkpoint system prevents ...
The ADEBAR trial: Final toxicity analysis of a phase III study evaluating the role of docetaxel in the adjuvant therapy of breast cancer patients with extensive lymph node involvement No significant ...
Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19 Nature, Gachet et al., at the ...
An open-label, phase II study of tipifarnib for the treatment of HRAS mutant solid tumors, including squamous cell carcinomas of the head and neck. Background: TTK (MPS1), a dual-specificity ...
The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers on all aspects of cellular structure and function ...
Timelapse of a gene-edited medaka fish embryo undergoing mitosis. The mitotic spindle – the green strands in the middle of the cells – can be seen aligning and segregating duplicated chromosomes, ...
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