Palisade Bio’s PDE4 inhibitor to treat the inflammatory bowel disease ulcerative colitis appears to be effective in mice, according to new data. Twice-daily doses of Palisade's oral prodrug PALI-2108 ...
A variant of the Aeromonas bacterium promoted colon inflammation in mice and was detected in stools and colon tissue from patients with ulcerative colitis (UC). Suspecting that gut-resident ...