Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

IBD has become a global disease in the 21st century that shifts through four epidemiological stages. Alterations in the gut ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disorder worldwide, reflecting the growing prevalence of obesity and type 2 diabetes. Some patients ...

Correspondence to Dr Leon M G Moons, Department of Gastroenterology and Hepatology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht 3508 GA, The Netherlands; ...

Dr L Lundell, Department of Surgery, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden. BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify patients exposed to ...

1 Department of Upper Gastro-intestinal Surgery, Hope Hospital, Salford Royal Hospitals NHS Trust, Manchester, UK 2 Department of Pathology, Hope Hospital, Salford Royal Hospitals NHS Trust, ...

A recent study by Erkert et al identified a new role for Alzheimer’s disease (AD)-associated presenilins as key molecules involved in maintaining intestinal epithelial function, barrier integrity and ...

1 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK 2 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK and Molecular Pathology Centre, Institute of ...

2 Inserm U954, Genetic Nutrition and Exposure to Environmental Risks (NGERE), University of Lorraine, Vandoeuvre- lès-Nancy, France Correspondence to Professor Laurent Peyrin-Biroulet, Inserm U954 and ...

Objective In the liver, the transcription factor, Kruppel-like factor 2 (KLF2), is induced early during progression of cirrhosis to lessen the development of vascular dysfunction; nevertheless, its ...

Department of Pathology, University Hospital Gasthuisberg, Catholic University Leuven, Belgium Dr D Sifrim, Faculty of Medicine, KU Leuven, Lab G-I Physiopathology, O & N Gasthuisberg 1, Herestraat 49 ...