Oct 9, 2022; Charlotte, North Carolina, USA; San Francisco 49ers running back Jeff Wilson Jr. (22) runs for yardage pursued by Carolina Panthers cornerback Jaycee Horn (8) during the first quarter at Bank of America Stadium. / Jim Dedmon-Imagn Images

For Panthers vs. 49ers on 'Monday Night Football,' the model is leaning Over the total, projecting 52 combined points. It also says one side of the spread hits well over 50% of the time in an A-rated pick. See what it is at SportsLine, and use promo code CHAMPIONSHIP to get your first month at SportsLine for $1.

Carolina will be missing multiple starters on defense as well as a big absence in the middle of their offensive line.

San Francisco 49ers star tight end George Kittle reflects on the blockbuster trade with the Carolina Panthers to land Christian McCaffrey.

The San Francisco 49ers had a productive offense under coach Kyle Shanahan for a while when the team made the big deal to acquire Christian McCaffrey from Carolina three years ago. The addition of one of the NFL's best dual-threat backs ever elevated that offense to another level that will be on display for the Panthers

San Francisco 49ers running back Christian McCaffrey, the NFL's leader in yards from scrimmage, could be in line to lay the wood on his former team, the Carolina Panthers, on Monday night.

Starting Thursday, you'll be able to support the Carolina Panthers and Luke Combs at the same time.Die-hard Panthers fan Luke has partnered with the team for an exclusive merchandise collaboration, which will drop Thursday at 11 a.

What comes after this season is over. though? While Hubbard is still under contract several more years, Dowdle will become a free agent in March. Asked by ESPN if he has had any contract talks with the team yet on Thursday, Dowdle had a simple answer.