The San Francisco 49ers have a big matchup against the Carolina Panthers that will swing the playoff odds in a big way. If ...

The San Francisco 49ers had a productive offense under coach Kyle Shanahan for a while when the team made the big deal to ...

Christian McCaffrey isn't the only 49er the Panthers have to contain. They'll also have to limit the Brock Purdy-to-George ...

If the Panthers want to come out victorious in their first prime-time showcase since 2023, they'll have to go through an old ...

Our favorite Panthers vs. 49ers prop picks for Monday Night Football are highlighted by star TE George Kittle.

The 49ers (7-4) are seeking a second straight win Monday night when they host the upstart Carolina Panthers (6-5).

San Francisco 49ers running back Christian McCaffrey, the NFL's leader in yards from scrimmage, could be in line to lay the ...

Ohio State Buckeyes defensive back Caleb Downs (2) celebrates with safety Jaylen McClain (18), linebacker Sonny Styles (0) ...

Carolina will be missing multiple starters on defense as well as a big absence in the middle of their offensive line.

The Panthers cannot beat the 49ers. Don’t misconstrue that: The Panthers can win on Monday. They have won six times already ...

Find single game tickets to the San Francisco 49ers vs. Carolina Panthers NFL Week 12 matchup on Monday, November 24, 2025 at ...

NFL Week 12 odds, picks, predictions, TV channel, streaming information for Monday Night Football between Carolina Panthers ...