49ers vs. Panthers will be on "Monday Night Football" in Week 12, which will air nationally on both ABC and ESPN. Joe Buck ...

The 49ers’ injuries have hurt their pass defense, with Bosa not there to rush on passing downs, and Warner no longer ...

The Carolina Panthers and San Francisco 49ers get to cap off the Week 12 slate with what is, surprisingly, a crucial game for ...

The Los Angeles Rams trounced the Tampa Bay Buccaneers, 34-7, on Sunday Night Football on NBC in Week 12. Rams quarterback ...

The 49ers (7-4) are seeking a second straight win Monday night when they host the upstart Carolina Panthers (6-5).

Carolina and quarterback Bryce Young hope to thrust themselves into national spotlight against 49ers on Monday Night Football ...

The Niners are coming off a win over the Arizona Cardinals in which the offense looked full-strength with Brock Purdy and ...

The 49ers welcome the Panthers for a Week 12 prime-time clash between two teams working to secure a playoff spot.

USA Today's NFL experts make their picks for a Week 12 showdown between the San Francisco 49ers and Carolina Panthers ...

Carolina is coming off a huge emotional win over Atlanta, but a much tougher opponent is lurking next on the schedule.

The San Francisco 49ers are back in playoff contention with Brock Purdy returning as their starting quarterback.

For Panthers vs. 49ers on 'Monday Night Football,' the model is leaning Over the total, projecting 52 combined points. It also says one side of the spread hits well over 50% of the time in an A-rated ...