Background Children and their parents report poor sleep in hospital and complain about noise. Objective To measure sleep quality and noise levels in hospital and compare these with the home ...

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

The relief of pain and anxiety associated with painful or invasive procedures is a top priority in paediatrics. A ‘Sounding Board’ in the New England Journal of Medicine 30 years ago stated that ‘The ...

Nirsevimab, a long-acting monoclonal antibody, was introduced last season (2023–2024) in some countries with the aim of reducing the burden of disease caused by respiratory syncytial virus (RSV) in ...

Aim To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1–16 years. Methods A national prospective population-based cohort study ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant expression of 15q11.2-q13 imprinted genes. Due to their rarity, data on ...

Objective To evaluate the efficacy differentials among corticosteroid regimens by type, dosage and duration, we conducted a systematic review and network meta-analysis of randomised controlled trials ...

Population and data. The CHiCS cohort and study design have been described in detail previously.18 The cohort includes 13 830 children and young people who were in care between August 2009 and July ...

Objectives To evaluate the appropriateness of the American Academy of Pediatrics’ (AAP) recommendation to no longer collect a urine culture (UC) in febrile infants ≥21 days old with negative ...

A 3-week-old infant is diagnosed with tuberous sclerosis complex (TSC) after cardiac rhabdomyomas are detected on prenatal ultrasound and a pathogenic variant in TSC2 is confirmed postnatally through ...

Objective Body mass index (BMI), and its adjustment for age and sex as a z-score, is a common measure of excess weight but performs poorly in children. Waist circumference to height ratio (WHtR), ...