In this issue of The EMBO Journal, Pizzagalli and colleagues present proof-of-principle analyses of immune cell motility ...

AdipoR1 selectively recognizes adipokine ligands, differentially shaping T-cell immune outcomes. CTRP9 engages AdipoR1 to ...

Over the past decade, several tumor-based predictors of cetuximab efficacy have been identified, yet most function as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Centrosomes are tubulin-based organelles that ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The compositional perturbation autoencoder ...

A plethora of endocrine disrupting chemicals (EDCs)—omnipresent in food, household, and personal care products—interfere with various human sperm functions and thus might impair fertilization.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chemical and genetic perturbations, such as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Gli1 + chondrogenic progenitors maintained by ...

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) innate immune pathway has emerged as a critical driver of inflammation in a variety of settings, such as virus infection, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The HSP110/HSP70 chaperone system plays key ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Many years ago, in the 1980s, my lab was ...

Autophagy is the cellular homeostatic pathway that delivers large cytosolic materials for degradation in the lysosome. Recent evidence indicates that autophagy mediates selective removal of protein ...