Improvements in medical therapy, carotid-artery stenting, and carotid endarterectomy call into question the preferred ...

Explore the current issue of The New England Journal of Medicine (Vol. 393 No. 20).

A 26-year-old woman was referred to the pulmonary hypertension clinic with a 6-month history of exertional dyspnea and hoarseness. Vocal-fold paralysis was seen on laryngoscopy (shown in a video).

A 79-year-old man was admitted to a hospital in Guangzhou, China, with progressive dyspnea and edema. Echocardiography and ...

Personalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The FDA outlines a path to market entry for products where a randomized trial is no ...

To the Editor: The results of the C-POST trial, reported by Rischin and colleagues (August 21/28 issue), 1 highlight improvements in disease-free survival with adjuvant cemiplimab. As the authors ...

Both tobevibart (a monoclonal antibody) and elebsiran (a small interfering RNA) target hepatitis B virus surface antigen ...

We conducted an international, open-label, randomized, blinded-outcome-assessment trial involving 1284 patients who had undergone successful catheter ablation for atrial fibrillation at least 1 year ...

Approaches to early detection of cancer often seem contentious, but the big-picture view is actually one of remarkable consensus. All major guideline groups recommend the Papanicolaou smear, ...

This feature about a student with strep throat and an unconfirmed penicillin allergy offers a case vignette accompanied by two essays, one supporting use of a nonpenicillin antibiotic and the other ...

In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy led to drug-free remission and mucosal healing, suggesting that B-cell targeting may offer a novel therapeutic pathway ...