Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium(III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...

During oogenesis, maternally derived protein/mRNA (e.g. Oskar, Vasa, Aubergine, Tudor) localize to the posterior pole for the formation of the germ plasm which possess the ability to induce primordial ...

This study was supported in part by Grants-in-Aid for Research on Innovative Areas from the Ministry of Education, Culture, Sports, Science and Technology, Japan (KAKENHI Grant No. JP16H06452 to T.D.) ...

As the EPA’s independent science arm, ORD ensures that agency decisions are grounded in the best available science. To meet mandates like the Clean Air and Clean Water Acts, ORD’s scientists work with ...

PNAS: Welcome to Science Sessions, the podcast of the Proceedings of the National Academy of Sciences, where we connect you with Academy members, researchers, and policymakers.Join us as we explore ...

Nav1.8 sodium channels are highly expressed in primary pain-sensing neurons. Suzetrigine is a potent and highly selective Nav1.8 inhibitor that has recently been approved by the Food and Drug ...

Green pigmentation provides a wide variety of animals with the ability to camouflage themselves among green vegetation. The molecular mechanisms of green coloration in insects are not well-understood, ...

To better understand the potential health threats and underlying visual pathways of long-term light at night (LAN) exposure, we adopted a widely accepted diurnal animal model tree shrew (Tupaia ...

Turbulence at centimeter scales plays a pivotal role in shaping the overturning circulation of the deep ocean (1, 2), as well as the ocean’s capacity to distribute and store climate-critical tracers ...

High-resistant starch (RS)/low-glutelin sbeIIb/Lgc1 lines were generated by CRISPR-Cas9-induced site-specific mutations in SBEIIb in an elite low-glutelin japonica rice cultivar ().According to this ...

We thank the Heflin Genomics Institute at UAB, UAB fish facility staff, the University of Massachusetts Chan Medical School (UMass Chan) fish facility, the Research Computing teams at the University ...