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6:55
YouTube
Onkoview
Hypoxia Inducible Factors (HIFs), Part 2: Regulation of HIF under normoxic and hypoxic conditions
The Hypoxia Inducible Factor (HIF) is a transcription factor, which consists of an alpha and a beta subunit. One of three alpha subunits dimerizes with one of two beta subunits. The alpha subunits are sensitive to oxygen, whereas the beta subunits are not. In this video, the domain structure of an HIF1α subunit is shown. A domain in the center ...
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