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An ischaemic stroke occurs when blood flow to part of the brain is suddenly reduced or blocked, most commonly by a blood clot. Because brain tissue depends on a constant supply of oxygen and glucose, interruption of blood flow leads to rapid neuronal injury and, if not reversed, permanent brain damage. What causes an ischaemic stroke Most ischaemic strokes are caused by one of the following mechanisms. A thrombotic stroke, where a clot forms locally in a narrowed cerebral artery, often related t
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