Metformin — How It Works and Why It’s First Line for Type 2 Diabetes
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Metformin — How It Works and Why It’s First Line for Type 2 Diabetes
Metformin is the first line drug for Type 2 Diabetes — but why? How it works: - Inhibits gluconeogenesis in liver - Increases insulin sensitivity in muscle & fat - Reduces glucose absorption in gut Result: Blood glucose improves Why first line? - Effective - Cheap - No weight gain - No hypoglycemia - Cardioprotective Avoid if eGFR is less ...
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